The ARC Research Hub for Driving Farming Productivity and Disease Prevention is funded through a prestigious and highly competitive Australian Research Council Industrial Transformation Research Hub Grant and focuses on driving industrial transformation in the agricultural sector. It has successfully fostered outstanding industry-research collaborations with five industry partners (Australian Bay Lobster Producers, Davco Agriculture, Sunray Strawberries, Aquarius Technologies and NextVPU), six Universities (Griffith University, The University of Adelaide, The University of Sydney, The University of Western Australia, Deakin University and Monash University) and the Commonwealth Scientific and Industrial Research Organisation (CSIRO). Through strong industry engagement and world-leading capabilities in image processing, machine learning, robotics, and software, together with expertise in engineering, agronomy, biology, water use, and farming technology, the Hub has already achieved significant success by advancing and incorporating new artificial intelligence (AI) technologies into industrial deployment in both testing and production environments including on-farm AI-based quality control. Adopted innovations have improved efficiency and revolutionized the way business is carried out, promoting higher farming efficiencies and lower production and disease costs. The Hub’s work is of high impact and has proven potential to benefit food production and distribution on a global scale.